Description
Product Characteristics:
C9orf103 (chromosome 9 open reading frame 103), also known as gluconate kinase, is a 187 amino acid protein that belongs to the gluconokinase gntK/gntV family and catalyzes the conversion of ATP and D-gluconate to ADP and 6-D-gluconate. Existing as three alternatively spliced isoforms, the gene encoding C9orf103 maps to human chromosome 9q21.32. Chromosome 9 consists of about 145 million bases, represents 4 % of the human genome and encodes nearly 900 genes. Thought to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster.
Subcellular location: Cytoplasm
Synonyms: bA522I20.2, C9orf103, Chromosome 9 open reading frame 103, Glucokinase like protein, Gluconate kinase, Gluconokinase like protein, GNTK_HUMAN, IDNK, OTTHUMP00000021546, OTTHUMP00000021547, Probable gluconokinase, RP11-522I20.2.
Target Information: IDNK (IDNK Gluconokinase) is a Protein Coding gene. Diseases associated with IDNK include Gordon Holmes Syndrome. Among its related pathways are Metabolism and Carbon metabolism. Gene Ontology (GO) annotations related to this gene include kinase activity and gluconokinase activity